Enantioselective Pd-catalyzed hydrogenation of fluorinated imines: facile access to chiral fluorinated amines.
نویسندگان
چکیده
An enantioselective hydrogenation of simple fluorinated imines has been developed using Pd(OCOCF(3))(2)/(R)-Cl-MeO-BIPHEP as a catalyst, and up to 94% ee was achieved. This method provides an efficient route to enantioenriched fluorinated amines.
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ورودعنوان ژورنال:
- Organic letters
دوره 12 21 شماره
صفحات -
تاریخ انتشار 2010